Consumption of dried fruit of Crataegus pinnatifida (hawthorn) suppresses high cholesterol diet-induced hypercholesterolemia in rats
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The effects of Crataegus pinnatifida (Chinese hawthorn) on metabolic syndrome: A review
Metabolic syndrome is described as a group of risk factors in which at least three unhealthy medical conditions, including obesity, high blood sugar, hypertension or dyslipidemia occur simultaneously in a patient. These conditions raise the risk for diabetes mellitus and cardiovascular diseases. Many recent studies have focused on herbal remedies and their pharmacological effects on metabolic s...
متن کاملPolyphenolic profile and biological activity of Chinese hawthorn (Crataegus pinnatifida BUNGE) fruits.
Chinese hawthorn (Crataegus pinnatifida Bge.) fruits are rich in polyphenols (e.g., epicatechin, procyanidin B2, procyanidin B5, procyanidin C1, hyperoside, isoquercitrin and chlorogenic acid)--active compounds that exert beneficial effects. This review summarizes all information available on polyphenolic content and methods for their quantification in Chinese hawthorn berries and the relations...
متن کاملبررسی اثرات عصاره هیدروالکلی میوه زالزالک و داروی آتورواستاتین بر روی بافت کبد موشهای صحرایی ماده مبتلا به هیپرکلسترولمی
Introdution:. Increased plasma cholesterol causes hepatic damages through oxidative stress (OS) induction. There are many investigations about hawthorn effects on lipid reduction and atherosclerosis. The goal of current study was to determine the effects of hydro-alcoholic extract of Crataegus aronia fruit (HECA) and atorvastatin (AVS) on hypercholesterolemia-induced alterations in serum lipid ...
متن کاملTriterpenic Acids Present in Hawthorn Lower Plasma Cholesterol by Inhibiting Intestinal ACAT Activity in Hamsters
Hawthorn (Crataegus pinnatifida) is an edible fruit used in traditional Chinese medicine to lower plasma lipids. This study explored lipid-lowering compounds and underlying mechanisms of action of hawthorn. Hawthorn powder extracts inhibited acylCoA:cholesterol acyltransferase (ACAT) activity in Caco-2 cells. The inhibitory activity was positively associated with triterpenic acid (i.e., oleanol...
متن کاملA Herbal Formula HT048, Citrus unshiu and Crataegus pinnatifida, Prevents Obesity by Inhibiting Adipogenesis and Lipogenesis in 3T3-L1 Preadipocytes and HFD-Induced Obese Rats.
HT048 is a combination composed of Crataegus pinnatifida leaf and Citrus unshiu peel extracts. This study aimed to investigate potential anti-obesity effect of the combination. The 3T3-L1 adipocytes were treated with different doses of HT048 and triglyceride accumulation, glycerol release and adipogenesis-related genes were analyzed. For in vivo study, male Sprague Dawley rats were divided acco...
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